:root{
  --ink:#2b2f2e; --muted:#6b7370; --line:#e6e8e4; --bg:#fff; --tint:#f6f7f4;
  --accent:#4f6b5f; --accent-dark:#3b5248;
  --serif:'Shippori Mincho',serif; --sans:'Noto Sans JP',sans-serif; --en:'Cormorant Garamond',serif;
  --header-h:72px;
}
*{box-sizing:border-box;margin:0;padding:0}
html{scroll-behavior:smooth;scroll-padding-top:var(--header-h)}
body{font-family:var(--sans);color:var(--ink);background:var(--bg);line-height:1.9;font-weight:400;-webkit-font-smoothing:antialiased}
img{max-width:100%;height:auto;display:block}
a{color:inherit}
ul,ol{list-style:none}
.container{width:min(1080px,100% - 48px);margin-inline:auto}
.container.narrow{width:min(720px,100% - 48px)}
.center{text-align:center}

/* Header */
.site-header{position:fixed;inset:0 0 auto 0;height:var(--header-h);background:rgba(255,255,255,.94);backdrop-filter:blur(8px);border-bottom:1px solid var(--line);z-index:100}
.header-inner{height:100%;width:min(1240px,100% - 40px);margin-inline:auto;display:flex;align-items:center;justify-content:space-between;gap:16px}
.logo img{height:44px;width:auto}
.gnav{display:flex;align-items:center;gap:24px}
.gnav ul{display:flex;gap:20px}
.gnav ul a{text-decoration:none;font-size:13px;letter-spacing:.04em;white-space:nowrap;padding:6px 0;border-bottom:1px solid transparent;transition:.2s}
.gnav ul a:hover{border-color:var(--accent);color:var(--accent)}
.menu-toggle{display:none;width:44px;height:44px;background:none;border:0;cursor:pointer;position:relative}
.menu-toggle span{position:absolute;left:10px;right:10px;height:1px;background:var(--ink);transition:.25s}
.menu-toggle span:nth-child(1){top:18px}.menu-toggle span:nth-child(2){top:26px}
.menu-toggle[aria-expanded="true"] span:nth-child(1){top:22px;transform:rotate(45deg)}
.menu-toggle[aria-expanded="true"] span:nth-child(2){top:22px;transform:rotate(-45deg)}

/* Buttons */
.btn{display:inline-block;padding:15px 32px;font-size:14px;letter-spacing:.06em;text-decoration:none;border:1px solid var(--accent);border-radius:2px;transition:.25s;cursor:pointer;font-family:inherit;text-align:center;line-height:1.5}
.btn-primary{background:var(--accent);color:#fff}
.btn-primary:hover{background:var(--accent-dark);border-color:var(--accent-dark)}
.btn-outline{background:transparent;color:var(--accent)}
.btn-outline:hover{background:var(--accent);color:#fff}
.btn-sm{padding:10px 20px;font-size:13px;white-space:nowrap}
.btn-block{display:block;width:100%}

/* Typography */
.eyebrow{font-family:var(--en);font-size:15px;letter-spacing:.24em;color:var(--accent);margin-bottom:12px;text-transform:uppercase}
/* 見出しを細身（400）の上品なしっぽり明朝に統一 */
h1,h2,h3{font-family:var(--serif);font-weight:400;line-height:1.6}
h2{font-size:clamp(24px,3.4vw,32px);letter-spacing:.05em}
h3{font-size:clamp(17px,2vw,20px)}
.section{padding:clamp(72px,10vw,120px) 0}
.section-tint{background:var(--tint)}
.section-head{text-align:center;margin-bottom:clamp(40px,6vw,64px)}
.section-sub{margin-top:16px;color:var(--muted);font-size:14px}

/* Hero */
.hero{padding-top:var(--header-h)}
.hero-inner{padding:clamp(56px,9vw,110px) 0 clamp(40px,6vw,64px);text-align:center}
.hero h1{font-size:clamp(26px,5vw,46px);letter-spacing:.06em;margin-bottom:32px}
.hero-lead{max-width:680px;margin-inline:auto;font-size:15px;color:#434a47}
.hero-lead p+p{margin-top:14px}
/* 本文引用テキストは角ばったゴシック体（Noto Sans JP）で読みやすく表示 */
.hero-quote{font-family:var(--sans);font-size:clamp(15px,2vw,18px);color:var(--ink)}
.hero-cta{margin-top:40px;display:flex;gap:16px;justify-content:center;flex-wrap:wrap}
.hero-visual img{width:100%;max-height:300px;object-fit:cover}

/* Cards */
.cards-3{display:grid;grid-template-columns:repeat(3,1fr);gap:28px}
.cards-2{display:grid;grid-template-columns:repeat(2,1fr);gap:32px}
.card{background:#fff;border:1px solid var(--line);padding:36px 30px;display:flex;flex-direction:column}
.case-no{font-family:var(--en);font-size:30px;color:var(--accent);line-height:1;margin-bottom:16px}
.card h3{margin-bottom:16px}
.card p{font-size:14px;color:#4a514e;flex:1}
.card-link{margin-top:24px;font-size:13px;color:var(--accent);text-decoration:none;border-bottom:1px solid var(--accent);align-self:flex-start;padding-bottom:2px}
.card-link:hover{opacity:.7}

/* Reasons */
.reason{max-width:900px;margin:0 auto clamp(56px,8vw,88px);text-align:center}
.reason:last-child{margin-bottom:0}
.reason-no{font-family:var(--en);letter-spacing:.2em;color:var(--accent);font-size:15px;display:block;margin-bottom:8px}
.reason h3{margin-bottom:20px;font-size:clamp(19px,2.6vw,24px)}
.reason p{text-align:left;font-size:15px}
.diagram{margin:36px auto 0;max-width:900px}
.diagram img{width:100%;border:1px solid var(--line);background:#fff}

/* Services */
.cat-grid{display:grid;grid-template-columns:repeat(5,1fr);gap:12px;margin-bottom:0}
.cat-card{position:relative;background:#fff;border:1px solid var(--line);padding:24px 12px;text-align:center;cursor:pointer;font-family:inherit;color:var(--ink);transition:.25s;display:flex;flex-direction:column;gap:4px;align-items:center}
.cat-card:hover{border-color:var(--accent)}
.cat-card[aria-selected="true"]{background:var(--accent);color:#fff;border-color:var(--accent)}
.cat-en{font-family:var(--en);font-size:14px;letter-spacing:.14em;opacity:.8}
/* カテゴリカードの日本語は角ばったゴシック体（Noto Sans JP）に変更 */
.cat-name{font-family:var(--sans);font-size:16px;font-weight:500}
.cat-badge{position:absolute;top:-10px;right:10px;background:#c9a96a;color:#fff;font-size:11px;padding:1px 10px;letter-spacing:.1em}
.cat-panels{background:#fff;border:1px solid var(--line);border-top:0;padding:32px;text-align:center;margin-top:12px;border-top:1px solid var(--line)}
.cat-panel[hidden]{display:none}
.cat-panel h3{margin-bottom:18px}
.cat-panel{animation:fadeIn .35s}
@keyframes fadeIn{from{opacity:0;transform:translateY(6px)}to{opacity:1;transform:none}}
.tags{display:flex;flex-wrap:wrap;gap:10px;justify-content:center}
.tags li{border:1px solid var(--line);background:var(--tint);padding:6px 18px;font-size:14px;border-radius:999px}
.tags small{color:var(--muted);font-size:12px;margin-left:4px}
.note-text{margin-top:16px;font-size:12px;color:var(--muted);text-align:center}
.service-blocks{margin-top:72px;display:grid;gap:28px}
.service-block{background:var(--tint);padding:clamp(28px,4vw,48px);border-left:2px solid var(--accent)}
.service-block h3{margin-bottom:16px}
.service-block p:last-child{font-size:14.5px;color:#434a47}

/* Steps */
.steps{display:grid;grid-template-columns:repeat(5,1fr);gap:16px;margin-bottom:clamp(72px,10vw,110px)}
.step{background:#fff;border:1px solid var(--line);padding:26px 20px}
.step-no{font-family:var(--en);color:var(--accent);font-size:20px;letter-spacing:.1em;display:block;margin-bottom:8px}
.step h3{font-size:15px;margin-bottom:10px}
.step p{font-size:13px;color:#4a514e;line-height:1.8}
.faq-head{margin-bottom:36px}
.faq{max-width:780px;margin:0 auto;border-top:1px solid var(--line)}
.faq-item{border-bottom:1px solid var(--line);background:#fff}
.faq-item summary{list-style:none;cursor:pointer;padding:22px 52px 22px 56px;position:relative;font-size:15px;font-weight:500}
.faq-item summary::-webkit-details-marker{display:none}
.faq-item summary::before{content:"Q";position:absolute;left:20px;font-family:var(--en);font-size:22px;color:var(--accent);top:17px}
.faq-item summary::after{content:"+";position:absolute;right:22px;top:50%;transform:translateY(-50%);font-size:22px;color:var(--accent);transition:.25s}
.faq-item[open] summary::after{content:"−"}
.faq-item p{padding:0 28px 24px 56px;font-size:14px;color:#4a514e;position:relative}
.faq-item p::before{content:"A";position:absolute;left:20px;font-family:var(--en);font-size:22px;color:#c9a96a;top:-4px}

/* Original products */
.product{text-align:center}
.product-img{aspect-ratio:4/3;background:linear-gradient(135deg,#f1f3ee,#e7ebe5);display:flex;align-items:center;justify-content:center;margin-bottom:20px;border:1px solid var(--line)}
.product-img span{font-family:var(--en);font-size:24px;letter-spacing:.24em;color:#9aa59f}
.status{font-size:13px;color:var(--muted);margin-top:4px;letter-spacing:.08em}

/* note */
.article{display:block;background:#fff;border:1px solid var(--line);text-decoration:none;transition:.25s;overflow:hidden}
.article:hover{transform:translateY(-3px);box-shadow:0 10px 24px rgba(0,0,0,.06)}
.article-thumb{aspect-ratio:16/9;background:linear-gradient(135deg,#eef1ec,#e1e7df);display:flex;align-items:center;justify-content:center;font-family:var(--en);letter-spacing:.2em;color:#9aa59f;font-size:22px;overflow:hidden}
.article-thumb img{width:100%;height:100%;object-fit:cover}
.article-body{padding:20px 22px 24px}
.article-date{font-family:var(--en);font-size:14px;color:var(--muted);letter-spacing:.08em;display:block;min-height:1.5em}
.article-body h3{font-family:var(--sans);font-size:14.5px;font-weight:500;line-height:1.75;margin-top:6px}
.topics{margin-top:80px;max-width:780px;margin-inline:auto}
.topics-title{text-align:center;font-size:22px;margin-bottom:24px}
.topics-title small{font-family:var(--sans);font-size:12px;color:var(--muted);margin-left:8px}
.topics-list{background:#fff;border-top:1px solid var(--line);margin-bottom:32px}
.topics-list li{border-bottom:1px solid var(--line)}
.topics-list a{display:flex;gap:24px;padding:18px 20px;text-decoration:none;font-size:14px;transition:.2s}
.topics-list a:hover{background:var(--tint);color:var(--accent)}
.topics-list time{font-family:var(--en);color:var(--muted);font-size:15px;flex-shrink:0;letter-spacing:.06em}
.topics-loading{padding:20px;text-align:center;color:var(--muted);font-size:13px}

/* Company */
.bases{margin-bottom:56px}
.base{border:1px solid var(--line);background:#fff}
.base img{width:100%;aspect-ratio:16/10;object-fit:cover}
.base-body{padding:28px 28px 32px;display:flex;flex-direction:column;align-items:flex-start;gap:12px}
.base-body p{font-size:14px}
.badge{display:inline-block;background:var(--tint);color:var(--accent);border:1px solid var(--accent);font-size:12px!important;padding:2px 12px;letter-spacing:.06em}
.placeholder{color:var(--muted)}
.profile{display:grid;grid-template-columns:160px 1fr;gap:36px;align-items:center;max-width:780px;margin-inline:auto;padding-top:48px;border-top:1px solid var(--line)}
.profile img{width:160px;aspect-ratio:1/1.1;object-fit:cover;border-radius:2px}
.profile dl>div{display:grid;grid-template-columns:90px 1fr;padding:10px 0;border-bottom:1px solid var(--line);font-size:14px}
.profile dt{color:var(--muted)}
.profile a{color:var(--accent)}

/* Form */
.mail-direct{margin-top:12px;font-size:18px}
.mail-direct a{color:var(--accent);border-bottom:1px solid var(--accent);text-decoration:none;word-break:break-all}
.form{background:#fff;padding:clamp(24px,5vw,48px);border:1px solid var(--line)}
.field{margin-bottom:24px;border:0}
.field>label,.field legend{display:block;font-size:14px;font-weight:500;margin-bottom:8px}
.field em{font-style:normal;background:#b4584a;color:#fff;font-size:11px;padding:1px 8px;margin-left:8px;border-radius:2px}
.opt{color:var(--muted);font-size:12px;margin-left:8px;font-weight:400}
.field input[type=text],.field input[type=email],.field input[type=tel],.field textarea{width:100%;padding:13px 14px;border:1px solid #cfd4d0;border-radius:2px;font-size:16px;font-family:inherit;background:#fff;transition:.2s}
.field input:focus,.field textarea:focus{outline:0;border-color:var(--accent);box-shadow:0 0 0 3px rgba(79,107,95,.15)}
.radios{display:grid;grid-template-columns:1fr 1fr;gap:10px}
.radios label{cursor:pointer}
.radios input{position:absolute;opacity:0}
.radios span{display:block;padding:12px 14px;border:1px solid #cfd4d0;font-size:14px;text-align:center;transition:.2s;border-radius:2px}
.radios input:checked+span{background:var(--accent);color:#fff;border-color:var(--accent)}
.radios input:focus-visible+span{box-shadow:0 0 0 3px rgba(79,107,95,.25)}
.hp{position:absolute;left:-9999px;width:1px;height:1px;overflow:hidden}
.form-caution{font-size:12.5px;color:var(--muted);margin-bottom:14px}
.agree{display:flex;gap:10px;align-items:center;font-size:14px;margin-bottom:28px;cursor:pointer}
.agree input{width:18px;height:18px;accent-color:var(--accent)}
.form-error{margin-top:16px;color:#b4584a;font-size:14px}
.form-done{background:#fff;border:1px solid var(--accent);padding:56px 24px;text-align:center}
.form-done h3{color:var(--accent);margin-bottom:12px;font-size:22px}
[hidden]{display:none!important}

/* Footer */
.site-footer{padding:48px 0;text-align:center;border-top:1px solid var(--line)}
.footer-logo{height:40px;width:auto;margin:0 auto 16px}
.site-footer small{color:var(--muted);font-size:12px}

/* Fade */
.fade{opacity:0;transform:translateY(16px);transition:opacity .8s,transform .8s}
.fade.in{opacity:1;transform:none}
@media (prefers-reduced-motion:reduce){.fade{opacity:1;transform:none;transition:none}html{scroll-behavior:auto}}

/* Responsive */
@media (max-width:1180px){
  .gnav ul{gap:14px}.gnav ul a{font-size:12px}.gnav{gap:14px}
}
@media (max-width:1040px){
  .menu-toggle{display:block}
  .gnav{position:fixed;top:var(--header-h);left:0;right:0;background:#fff;flex-direction:column;align-items:stretch;padding:12px 24px 28px;gap:20px;border-bottom:1px solid var(--line);transform:translateY(-120%);visibility:hidden;transition:.3s;max-height:calc(100vh - var(--header-h));overflow-y:auto}
  .gnav.open{transform:none;visibility:visible}
  .gnav ul{flex-direction:column;gap:0}
  .gnav ul a{display:block;padding:14px 0;border-bottom:1px solid var(--line);font-size:14px}
  .steps{grid-template-columns:repeat(3,1fr)}
  .cat-grid{grid-template-columns:repeat(3,1fr)}
}
@media (max-width:820px){
  .cards-3{grid-template-columns:1fr}
  .cards-2{grid-template-columns:1fr}
  .steps{grid-template-columns:1fr 1fr}
}
@media (max-width:560px){
  :root{--header-h:64px}
  .container,.container.narrow{width:calc(100% - 40px)}
  .logo img{height:38px}
  .cat-grid{grid-template-columns:1fr 1fr}
  .cat-card{padding:18px 8px}
  .steps{grid-template-columns:1fr}
  .radios{grid-template-columns:1fr}
  .profile{grid-template-columns:1fr;justify-items:center}
  .profile dl{width:100%}
  .profile dl>div{grid-template-columns:70px 1fr}
  .topics-list a{flex-direction:column;gap:4px}
  .hero-cta .btn{width:100%}
  .faq-item summary{padding:18px 44px 18px 48px;font-size:14px}
  .faq-item summary::before{left:16px;top:13px}
  .faq-item p{padding:0 20px 20px 48px}
  .faq-item p::before{left:16px}
  .cat-panels{padding:24px 16px}
}

/* ===== スマートフォン向け 日本語タイポグラフィ・改行制御 ===== */
h1, h2, h3, h4, p, span, a, label {
  word-break: normal;
  overflow-wrap: break-word;
}
.hero-title, .section-title, .card-title, .reason-title,
h1, h2, h3 {
  word-break: auto-phrase;
}

/* 図解画像枠消去 */
#reason figure, 
#reason .figure-container,
#reason .diagram img,
#reason img[src*="carriage_network"],
#reason img[src*="carriage_one_contact"] {
  border: none !important;
  box-shadow: none !important;
  background: transparent !important;
  padding: 0 !important;
}

/* ===== 8カテゴリー・処方開発/海外展開カード ===== */
.cat-grid{grid-template-columns:repeat(4,1fr);row-gap:20px}
.cat-card.is-main{border-color:var(--accent)}
.mini-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:16px;margin:24px 0}
.mini-card{background:#fff;border:1px solid var(--line);padding:20px}
.mini-card h4{font-size:15px;margin-bottom:8px}
.mini-card p{font-size:13.5px;color:#434a47}
.mini-no{display:block;font-family:var(--en);letter-spacing:.14em;color:var(--accent);font-size:13px;margin-bottom:4px}
@media (max-width:900px){
  .cat-grid{grid-template-columns:repeat(2,1fr)}
  .mini-grid{grid-template-columns:1fr}
}

/* 改行制御ユーティリティ */
.inline-block{display:inline-block}
br.sm\:hidden{display:inline}
.sm\:hidden{display:inline}
@media (min-width:640px){br.sm\:hidden{display:none}}
.text-base{font-size:16px}
@media (min-width:640px){.sm\:text-2xl{font-size:inherit}.sm\:font-serif{font-weight:inherit}}
.text-base.font-normal{font-weight:400}
/* ===== フォント統一：見出しのみしっぽり明朝(400)、それ以外はNoto Sans JP ===== */
body, button, input, textarea, select,
p, li, dl, dt, dd, h3, h4, .section-sub, .note-text, .hero-lead, .hero-quote, .btn {
  font-family: var(--sans);
}
h3, h4 { font-weight: 500; }
.cat-name {
  font-family: var(--sans) !important;
  font-weight: 500;
}
.hero h1,
.topics-title,
#problems h2,
#reason h2,
#service h2,
#flow h2,
.faq-head h2,
#original h2,
#note h2,
#company h2,
#contact h2 {
  font-family: var(--serif) !important;
  font-weight: 400 !important;
  letter-spacing: 0.05em;
}
.topics-title small { font-family: var(--sans) !important; font-weight: 400; }

/* ===== 小見出しを細身に ===== */
.reason h3,
#reason h3,
.service-block h3 {
  font-weight: 400 !important;
}

/* ===== ヒーローリード文をNoto Sans JPに統一 ===== */
.hero-lead,
.hero-lead p,
.hero-quote {
  font-family: var(--sans) !important;
  font-weight: 400 !important;
}